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US 2025/0034543 A1Published application
Penicillin-g acylases
AssigneeCodexis, Inc.
InventorsJovana Nazor, Vesna Mitchell, David Elgart, Katrina W. Lexa, Nikki Dellas, Robert Kevin Orr, Oscar Alvizo, Ravi David Garcia, Judy Victoria Antonio Viduya, Courtney Dianne Moffett
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Abstract
The present invention provides engineered penicillin G acylase (PGA) enzymes having improved properties, polynucleotides encoding such enzymes, compositions including the enzymes, and methods of using the enzymes.
Claims20
An engineered penicillin G acylase having a polypeptide sequence that is at least 95% identical to SEQ ID NO:
- 8, wherein said penicillin G acylase comprises a threonine residue at position X27 as compared to the sequence of SEQ ID NO:
- 8.
Dependencies are inferred from the claim text.