Microorganism and method for the improved production of valine
AssigneeMetabolic Explorer
InventorsPerrine VASSEUR, Thomas DESFOUGERES, Céline RAYNAUD
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Abstract
The present invention relates to a microorganism genetically modified for improved production of valine, wherein the microorganism overexpresses a ilvA gene coding a threonine deaminase and/or exhibits an increased threonine deaminase activity and comprises a mutated argP gene coding DNA-binding transcriptional dual regulator. The present invention also relates to a method for the production of valine using said microorganism.
Claims14
Microorganism genetically modified for the production of valine, wherein the microorganism overexpresses a ilvA gene coding a threonine deaminase and/or exhibits an increased threonine deaminase activity as compared to the expression level and/or threonine deaminase activity in a corresponding wild-type microorganism, and wherein the microorganism further comprises a mutated argP gene coding DNA-binding transcriptional dual regulator.
Dependencies are inferred from the claim text.