Use of mirna-2911 molecule as nucleic acid stabilizer
AssigneeLnctac Co., Ltd.
InventorsXiaoxia ZHANG, Miao ZENG
Life of this patent
Estimating the term…
Abstract
The present invention relates to a use of a miRNA-2911 molecule as a nucleic acid stabilizer. Specifically, the structure of the miRNA-2911 molecule for improving the stability of a target nucleic acid is shown in the following formula: GGX1X2GGGGG-(L)n-X3X4GGX5X6X7GGGX8 (SEQ ID NO: 1), wherein X1, X2, X3, X4, X5, X6, X7, and X8 are independently selected from A, C, T, and U; n is 0 or 1; and L represents a linker group having a length of no more than 10 nucleotides.
Claims12
A miRNA-2911 and the nucleic acid molecule derived therefrom for improving the stability of a nucleic acid of interest, wherein the nucleotide sequence of the miRNA-2911 and the nucleic acid molecule derived therefrom comprises the following nucleic acid sequence:
- (SEQ ID NO:
- 1)
- GGX1X2GGGGG-(L)n-X3X4GGX5X6X7GGGX8
- wherein:
- X1, X2, X3, X4, X5, X6, X7 and X8 are independently selected from A, C, T and U;
- n is zero or 1;
- L represents a linker group of no more than 10 nucleotides in length.
Dependencies are inferred from the claim text.