Anti-bcma nanobody and use thereof
OwnerYayuan Fu, Shumei You +4inventors
InventorsYayuan Fu, Shumei You, Bowei Yin, Zhuoxiao Cao, Renhong Tang, Jinsheng Ren
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Abstract
An antibody, or an antigen-binding fragment of same, specifically binding to a BCMA, a nucleic acid encoding same, an expression vector and an expression cell thereof, a preparation method therefor, a pharmaceutical composition thereof, and the use thereof in treating a disease, for example, the use thereof in treating a tumour.
Claims22
An antibody or an antigen-binding fragment thereof that specifically binds to BCMA, wherein the antibody or the antigen-binding fragment thereof comprises CDR1, CDR2 and CDR3, and the CDR1 comprises HCDR1 of a VHH domain as shown in any one of SEQ ID NOs:
- 7-21, 24-31 and 92-101, the CDR2 comprises HCDR2 of a VHH domain as shown in any one of SEQ ID NOs:
- 7-21, 24-31 and 92-101, and the CDR3 comprises HCDR3 of a VHH domain as shown in any one of SEQ ID NOs:
- 7-21, 24-31 and 92-101.
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Dependencies are inferred from the claim text.