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US 2025/0026802 A1Published application
Chimeric adiponectin polypeptides, extracellular vesicle comprising the same, and uses thereof
AssigneesCiloa, Jerid
InventorsZaïne El Abiddine Robert MAMOUN, Bernadette Nadine TRENTIN, Katarzyna POLAK
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Abstract
Chimeric polypeptides having an amino acid sequence of adiponectin and an amino acid sequence of a transmembrane domain of a transmembrane protein, nucleic acids encoding these chimeric polypeptides, and extracellular vesicles including these chimeric polypeptides. Also, the use of these extracellular vesicles as a medicament, and in particular, for treating various diseases, disorders or conditions.
Claims21
1-15. (canceled)
A chimeric polypeptide comprising, in any order:
- i) an amino acid sequence of adiponectin, and
- ii) an amino acid sequence of a transmembrane domain of a transmembrane protein.
Dependencies are inferred from the claim text.