Inferring lead placement based on sensed biomarkers
AssigneeBoston Scientific Neuromodulation Corporation
InventorsMax Witwer, Tianhe Zhang
Life of this patent
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Abstract
A system may include an electrode arrangement and a neurostimulator. The electrode arrangement may have a length generally in a rostral-caudal direction and a width generally in a mediolateral direction. The electrode arrangement may include a first set and a second set of electrodes spaced across the width. The neurostimulator may be configured to stimulate a sequence of locations of the patient using subsets of the first set of electrodes, and for each stimulated location in the stimulated sequence of locations identify corresponding response measures for each one of the second set of electrodes. The physiological midline may be inferred or identified from these measurements, which may be used to guide lead placement and/or programming.
Claims20
A method performed using an electrode arrangement positioned near a spine of a patient, wherein the electrode arrangement has a length generally in a rostral-caudal direction of the patient and a width generally in a mediolateral direction patient, and the electrode arrangement includes a first set of electrodes spaced across the width and a second set of electrodes spaced across the width, wherein the method includes:
- stimulating a sequence of locations of the patient using subsets of the first set of electrodes;
- for each stimulated location in the stimulated sequence of locations, identifying corresponding response measure for each electrode subset within the second set of electrodes, wherein
- the stimulated sequence of locations includes at least a first location and a second location and the second set of electrodes includes at least a first electrode subset and a second electrode subset,
- the corresponding response measures includes, for the first location, a first first-location response measure for the first electrode subset and a second first-location response measure for the second electrode subset, and
- the corresponding response measures includes, for the second location, a first second-location response measure for the first electrode subset and a second second-location response measure for the second electrode subset;
- and
- identifying a physiological midline based on the corresponding response measures for each stimulated location in the stimulated sequence of locations.
A non-transitory machine-readable medium including instructions, which when executed by a machine, cause the machine to perform a method using an electrode arrangement positioned near a spine of a patient, wherein the electrode arrangement has a length generally in a rostral-caudal direction of the patient and a width generally in a mediolateral direction patient, and the electrode arrangement includes a first set of electrodes spaced across the width and a second set of electrodes spaced across the width, wherein the method performed by the machine includes:
- stimulating a sequence of locations of the patient using subsets of the first set of electrodes;
- and
- for each stimulated location in the stimulated sequence of locations, identifying corresponding response measures for each electrode subset within the second set of electrodes, wherein
- the stimulated sequence of locations includes at least a first location and a second location and the second set of electrodes includes at least a first electrode subset and a second electrode subset,
- the corresponding response measures includes, for the first location, a first first-location response measure for the first electrode subset and a second first-location response measure for the second electrode subset, and
- the corresponding response measures includes, for the second location, a first second-location response measure for the first electrode subset and a second second-location response measure for the second electrode subset.
A system, comprising:
- an electrode arrangement configured to be positioned near a spine of a patient, wherein the electrode arrangement has a length generally in a rostral-caudal direction of the patient and a width generally in a mediolateral direction patient, and the electrode arrangement includes a first set of electrodes spaced across the width and a second set of electrodes spaced across the width;
- a neurostimulator configured to connect to the electrode arrangement and further configured to:
- stimulate a sequence of locations of the patient using subsets of the first set of electrodes;
- for each stimulated location in the stimulated sequence of locations, identify corresponding response measures for each electrode subset within the second set of electrodes, wherein
- the stimulated sequence of locations includes at least a first location and a second location and the second set of electrodes includes at least a first electrode subset and a second electrode subset,
- the corresponding response measures include, for the first location, a first first-location response measure for the first electrode subset and a second first-location response measure for the second electrode subset, and
- the corresponding response measures include, for the second location, a first second-location response measure for the first electrode subset and a second second-location response measure for the second electrode subset,
- wherein the system is configured to identify a physiological midline based on the corresponding response measures for each stimulated location in the stimulated sequence of locations.
Dependencies are inferred from the claim text.