# US 2025/0025629 A1 · Irrigation system and methods of use > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2025/0025629 A1 - Document ID: US20250025629A1 - Status: Published application - Kind: A1 - Application number: 18/909,211 - Filed: 2024-10-08 - Published: 2025-01-23 - Earliest claimed: 0001-01-01 - Assignees: Osteal Therapeutics, Inc. - Applicants: Osteal Therapeutics, Inc. - Inventors: Robert C. Hutton; Brian C. de Beaubien; Matthew Gill; Douglas Lorang; James McCrea; Jude Paganelli; Andrew Sauter; Michael Wong - Web page: https://patentgrep.com/patent/US20250025629A1 ## CPC - A61M 5/16809: {by repeated filling and emptying of an intermediate volume} - A61P 17/02: for treating wounds, ulcers, burns, scars, keloids, or the like - A61K 9/08: Solutions {(composition of solutions A61K47/00)} - A61K 31/4196: 1,2,4-Triazoles - A61K 31/7036: having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins - A61K 38/14: Peptides containing saccharide radicals; Derivatives thereof {, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin} - A61M 1/772: {operating alternately} - A61M 3/0202: {with electronic control means or interfaces} - A61M 5/1408: {in parallel, e.g. by manifolds or with sequencing valves} - A61M 5/1414: {Hanging-up devices} - A61M 5/16895: {by monitoring weight change, e.g. of infusion container} - A61P 31/04: Antibacterial agents - A61M 2005/14208: {with a programmable infusion control system, characterised by the infusion program} - A61M 2202/0007: introduced into the body - A61M 2202/0468: non-physiological - A61M 2205/3334: Measuring or controlling the flow rate - Y02A 50/30: Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} - A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS - A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D) - Y02A: TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE ## Abstract A treatment delivery system includes a fluid delivery system connected to a first fluid reservoir and a second fluid reservoir. The system directs a first fluid from the first fluid reservoir to a treatment site and directs a second fluid from the second fluid reservoir to the treatment site and a control unit to control the fluid delivery system according to a treatment process comprising a flow of the first fluid and the second fluid, the treatment process including multiple phases. A first phase includes a controlled delivery of the first fluid from the first fluid reservoir to the treatment site. A second phase of the plurality of phases includes a controlled delivery of the second fluid from the second fluid reservoir to the treatment site, the control unit automatically activating a transition from at least the first phase to the second phase. ## Claims ### Claim at position 1 -72. (canceled) ### Claim 73 A treatment delivery system for treating an infected treatment site of a patient, said system comprising: a fluid delivery system for directing a first fluid to the infected treatment site and for directing a second fluid to the infected treatment site; and a control unit programmed to control the fluid delivery system according to a treatment process comprising a plurality of phases, wherein a first phase of the treatment process comprises a controlled delivery of the first fluid to the infected treatment site, maintaining the first fluid at the infected treatment site for a first period of time, and removing a first site fluid from the infected treatment site, said first site fluid comprising at least some of the first fluid, a second phase of the treatment process comprises a controlled delivery of the second fluid to the infected treatment site, maintaining the second fluid at the infected treatment site for a second period of time, and removing a second site fluid from the infected treatment site, said second site fluid comprising at least some of the second fluid, and at least one third phase of the treatment process comprises repeating the second phase of the treatment process, wherein the treatment process of the control unit automatically activates a first transition from the first phase to the second phase, and a second transition from the second phase to the third phase, and wherein, after an initial user activation of the treatment process before the first phase, each of said first, second and third phases and the first and second transitions are caused to proceed without further user intervention or input. ### Claim 74 (depends on 73) The treatment delivery system of claim 73, wherein the at least one third phase of the treatment process comprises multiple repetitions of the second phase of the treatment process, wherein the treatment process transitions between the multiple repetitions of the second phase without user intervention or input. ### Claim 75 (depends on 74) The treatment delivery system of claim 74, wherein the treatment process comprises a fourth phase, wherein the fourth phase comprises repeating at least the first phase and the second phase of the treatment process, and wherein the treatment process transitions between the at least one third phase and the fourth phase without user intervention or input. ### Claim 76 (depends on 73) The treatment delivery system of claim 73, wherein the system comprises a first fluid reservoir and a second fluid reservoir, and wherein the first fluid is delivered from the first fluid reservoir to the infected treatment site and wherein the second fluid is delivered from the second fluid reservoir to the infected treatment site. ### Claim 77 (depends on 76) The treatment delivery system of claim 76, further comprising: a first load cell configured to detect a combined weight comprising a first weight of the first fluid and the first fluid reservoir and a second weight of the second fluid and the second fluid reservoir, wherein the control unit processes the combined weight measured at a first point in time and at a second point in time later than the first point, in order to monitor a status of fluid delivery. ### Claim 78 (depends on 77) The treatment delivery system of claim 77, wherein the status of fluid delivery comprises at least one of a first volume of the first fluid delivered from the first fluid reservoir and a second volume of the second fluid delivered from the second reservoir. ### Claim 79 (depends on 77) The treatment delivery system of claim 77, wherein the first load cell is arranged within a vertical plane of the system and is configured to be contacted horizontally by a cantilevered hanger component. ### Claim 80 (depends on 73) The treatment delivery system of claim 73, further comprising a waste fluid canister configured to collect the first site fluid and the second site fluid removed from the treatment site. ### Claim 81 (depends on 80) The treatment delivery system of claim 80, further comprising a second load cell configured to detect a waste weight of the waste fluid canister and any fluid within the canister, wherein the control unit processes the waste weight to monitor a status of fluid removal. ### Claim 82 (depends on 81) The treatment delivery system of claim 81, wherein when the waste weight equals or exceeds a threshold, an alarm is triggered to indicate the waste fluid canister is full. ### Claim 83 (depends on 81) The treatment delivery system of claim 81, wherein the second load cell is arranged within the vertical plane of the system and is configured to be contacted horizontally by a second cantilevered hanger component. ### Claim 84 (depends on 73) The treatment delivery system of claim 73, wherein the fluid delivery system further comprises at least one pinch valve controlled by the control unit to open and close according to the treatment process. ### Claim 85 (depends on 84) The treatment delivery system of claim 84, wherein the at least one pinch valve of the fluid delivery system comprises a first pinch valve and a second pinch valve, wherein the first pinch valve is configured to receive a first fluid delivery line adapted to be fluidly connected to a first fluid reservoir and the second pinch valve is configured to receive a second fluid delivery line adapted to be fluidly connected to a second fluid reservoir. ### Claim 86 (depends on 85) The treatment delivery system of claim 85, wherein the first pinch valve is controlled by the control unit to be open during the first phase and is controlled by the control unit to be closed during the second phase, wherein the second pinch valve is controlled by the control unit to be closed during the first phase and is controlled by the control unit to be open during the second phase. ### Claim 87 (depends on 85) The treatment delivery system of claim 85, wherein the first pinch valve has a first inner dimension when in an open configuration and wherein the second pinch valve has a second inner dimension when in an opening configuration, wherein the first inner dimension is different than the second inner dimension. ### Claim 88 (depends on 85) The treatment delivery system of claim 85, wherein the first fluid delivery line has a smaller outer dimension than the second fluid delivery line, the smaller outer dimension sized to be received within the first inner dimension of the first pinch valve. ### Claim 89 (depends on 85) The treatment delivery system of claim 85, wherein the second fluid delivery line has an outer dimension large enough to be unable to be received within the first inner dimension of the first pinch valve. ### Claim 90 (depends on 73) The treatment delivery system of claim 73, wherein the control unit comprises: a pump configured to generate a set vacuum pressure; and a valve configured to control a vacuum relief. ### Claim 91 (depends on 90) The treatment delivery system of claim 90, wherein the pump is powered off during at least the first phase. ### Claim 92 (depends on 90) The treatment delivery system of claim 90, wherein the pump is configured to run at an approximately constant voltage during a first period of time and at an approximately constant torque during a second period of time to generate the set vacuum pressure. ### Claim 93 (depends on 90) The treatment delivery system of claim 90, further comprising: a leak alarm configured to generate an alert indicating a pressure leak determined in response to the control unit detecting a vacuum pressure at the treatment site being below a threshold. ### Claim 94 (depends on 80) The treatment delivery system of claim 80, further comprising: a waste fluid canister fill sensor configured to generate a waste fluid canister fill alert indicating a fill level of the waste fluid canister being above a fill threshold during the treatment process, wherein the control unit stops removal of any of the first fluid and the second fluid from the treatment site in response to the collecting fluid canister fill alert. ### Claim 95 (depends on 77) The treatment delivery system of claim 77, further comprising: an empty fluid reservoir alarm configured to generate an alert indicating that a weight of the first fluid delivered or a weight of the second fluid delivered is below a minimum threshold corresponding to a respective phase of the plurality of phases. ### Claim 96 (depends on 73) The treatment delivery system of claim 73, further comprising: a low battery alarm configured to generate an alert indicating a charge level of a battery of the control unit, wherein the charge level of the battery is determined in response to the control unit detecting the charge level of the battery being below a minimum charge level adequate for powering automatic transition between the plurality of phases. ### Claim 97 (depends on 73) The treatment delivery system of claim 73, further comprising: an incorrect assembly alarm configured to generate an alert indicating an incorrect assembly of the treatment delivery system, wherein the incorrect assembly is determined in response to the control unit detecting a missing or incorrectly coupled component of the treatment delivery system that prevents an automatic transition between the plurality of phases. ### Claim 98 (depends on 73) The treatment delivery system of claim 73, further comprising: a motion alarm configured to pause fluid delivery and generate an alert indicating an excessive motion that affects a weight sensor reading during fluid delivery. ### Claim 99 (depends on 73) The treatment delivery system of claim 73, further comprising a user interface configured to receive a user input comprising a selection of an operation for initiating a sequence comprising the plurality of phases. ### Claim 100 (depends on 73) The treatment delivery system of claim 73, wherein the first fluid comprises tobramycin sulfate and the second fluid comprises vancomycin hydrochloride. ### Claim 101 (depends on 100) The treatment delivery system of claim 100, wherein the first period of time is different from the second period of time. ### Claim 102 (depends on 100) The treatment delivery system of claim 100, wherein the first period of time is longer than the second period of time.