Back to results
US 2025/0025525 A1Published application
Octapeptide for topical application
AssigneeAlastin Skincare, Inc.
InventorsAlan David WIDGEROW, John A. GARRUTO
Life of this patent
Estimating the term…
Abstract
Described herein are compositions and methods comprising one or more peptides including an octapeptide with amino acid sequence features found in collagen and/or elastin.
Claims20
A topical composition for stimulating synthesis of high MW HA, the composition comprising:
- a synthetic, isolated, or recombinant polypeptide comprising an amino acid sequence GPHGVREA (SEQ ID NO:1), GDGDGASA (SEQ ID NO:
- 2), GPMGPSGP (SEQ ID NO:
- 3), GLGPGARA (SEQ ID NO:
- 4), GPQGFQGP (SEQ ID NO:
- 5), GPMGPRGP (SEQ ID NO:
- 6), or GPGKNGDD (SEQ ID NO:
- 7), wherein the polypeptide comprises no more than 20 amino acids;
- a tripeptide-1;
- and
- a hexapeptide-12.
7 more elements
A method for reducing inflammation in skin of an individual, promoting skin repair, treating or restoring aging skin, treating a cutaneous wound, or promoting wound healing or wound closure, the method comprising:
- administering to the skin a composition comprising:
- a synthetic, isolated, or recombinant polypeptide comprising an amino acid sequence GPHGVREA (SEQ ID NO:1), GDGDGASA (SEQ ID NO:
- 2), GPMGPSGP (SEQ ID NO:
- 3), GLGPGARA (SEQ ID NO:
- 4), GPQGFQGP (SEQ ID NO:
- 5), GPMGPRGP (SEQ ID NO:
- 6), or GPGKNGDD (SEQ ID NO:
- 7), wherein the polypeptide comprises no more than 20 amino acids;
- a tripeptide-1;
- and
- a hexapeptide-12.
8 more elements
Dependencies are inferred from the claim text.