Combination therapies
AssigneeInfinity Pharmaceuticals, Inc.
InventorsJeffery L. KUTOK, Howard M. STERN
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Abstract
Provided herein are pharmaceutical compositions comprising a phosphatidylinositol 3-kinase inhibitor or a pharmaceutically acceptable form thereof, and a Bcl-2 inhibitor or a pharmaceutically acceptable form thereof. Also provided herein are methods for treating cancer comprising administration the compositions, and uses of the compositions, e.g., for the treatment of cancer.
Claims2
A composition for use in the treatment of a cancer, said composition comprising a synergistic combination of a PI3K inhibitor, or a pharmaceutically acceptable form thereof, wherein the PI3K inhibitor is (S)-3-(1-((9H-purin-6-yl)amino)ethyl)-8-chloro-2-phenylisoquinolin-1(2H)-one or (S)-2-(1-(9H-purin-6-ylamino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one;
- and a Bcl-2 inhibitor, or a pharmaceutically acceptable form thereof.
-87. (canceled)
Dependencies are inferred from the claim text.