Synergistic transport of lipophilic and hydrophilic active substances in nanoparticles

A nanocontainer, comprising

• a lipophilic core,
• wherein the lipophilic core comprises at least one lipophilic compound selected from a lipophilic, pharmaceutically active ingredient or a lipophilic detection reagent;
• and
• a hydrophilic shell enclosing the lipophilic core,
• wherein the hydrophilic shell is composed of an inorganic-organic hybrid compound as an ionic compound, wherein the inorganic-organic hybrid compound is composed of an inorganic metal cation selected from Mn2+, Sc3+, Y3+, La3+, Fe2+, Fe3+, [ZrO]2+, [HfO]2+, Bi3+, Gd3+ or a lanthanide Ln2+ or Ln3+ or a hydrated form of these cations, and an organic active ingredient anion or a hydrophilic detection reagent anion, each of which contains at least one phosphate, phosphonate, sulfate, sulfonate, carbonate or carboxylate group as a functional group,
• wherein a pharmaceutically active ingredient is a substance used as an agent for curing or preventing human or animal diseases, as well as a substance intended to be used in or on the human or animal body to restore, improve or influence human or animal body functions, and a detection reagent is a substance that can be detected/localized in the body after administration, for example optically via fluorescence in the case of a fluorescent dye or also through X-ray absorption, magnetic measurements or based on their radioactive radiation.