Wearable optical e-tattoo for arterial and venous blood oxygenation monitoring
AssigneeBoard of Regents, The University of Texas System
InventorsNanshu Lu, Philip Tan, Eric Wang, Sarnab Bhattacharya
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Abstract
Disclosed and described herein are systems, methods and device for providing simultaneous non-invasive arterial and venous oxygen saturation. An ultra-thin and self-adherable optical electronic tattoo measures blood absorbance changes from multiple locations. Another sensor may be included to provide self-calibration. Using algorithms, the signals from the blood from the artery and vein can be better separated and yield accurate blood oxygen assessments.
Claims24
A pressureless, non-invasive system for simultaneous extraction and measurement of arterial and venous blood oxygenation, comprising:
- a flexible electronic tattoo, said flexible electronic tattoo comprising:
- a flexible conformable substrate, wherein the substrate is configured to conform to and adhere to a location on a skin of a wearer;
- a plurality of optical oxygenation sensors mounted on the substrate, wherein the optical oxygenation sensors each non-invasively obtain information related to in-situ blood oxygenation from within a vein and/or artery of the wearer;
- a communications interface mounted on the interface, wherein the communications interface is in communication with the plurality of optical oxygenation sensors;
- and
- a power source mounted on the flexible conformable substrate;
- and
- one or more processors, wherein the one or more processors receive the information related to the in-situ blood oxygenation from within the vein and/or artery of the wearer through the communications interface and simultaneously extract venous blood oxygenation (SvO2) and arterial blood oxygenation (SaO2) from the information related to the in-situ blood oxygenation from within the vein and/or artery of the wearer.
A method for using a pressureless, non-invasive system for simultaneous extraction and measurement of arterial and venous blood oxygenation, the method comprising:
- attaching flexible electronic tattoo to an epidermis of a wearer, proximate an artery and a vein of the wearer, said flexible electronic tattoo comprising:
- a flexible conformable substrate, wherein the substrate is configured to conform to and adhere to a location on a skin of a wearer;
- a plurality of optical oxygenation sensors mounted on the substrate, wherein the optical oxygenation sensors each non-invasively obtain information related to in-situ blood oxygenation from within a vein and/or artery of the wearer;
- a communications interface mounted on the interface, wherein the communications interface is in communication with the plurality of optical oxygenation sensors;
- and
- a power source mounted on the flexible conformable substrate;
- and
- receiving, by one or more processors, the information related to the in-situ blood oxygenation from within the vein and/or artery of the wearer through the communications interface;
- and
- simultaneously extracting, by the one or more processors, venous blood oxygenation (SvO2) and arterial blood oxygenation (SaO2) from the information related to the in-situ blood oxygenation from within the vein and/or artery of the wearer.
Dependencies are inferred from the claim text.