Method for constructing strain for producing recombinant protein containing unnatural amino acids, and strain obtained therefrom
AssigneeNovocodex Biopharmaceuticals Co., Ltd.
InventorsLongfei Chen, Lin Jiao, Yuebin Ying, Zunyang Gong, Jingjing Zhu, Xuejun Liang
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Abstract
Provided in the present invention are a method for constructing a strain for producing a recombinant protein containing unnatural amino acids, and the strain obtained therefrom. The method comprises modifying the expression of a prfA gene contained in the strain to be controllable. The strain constructed by the method of the present invention can efficiently produce in intact protein containing unnatural amino acids, greatly reduce the production of a truncated protein and can also maintain high-speed growth.
Claims10
A method for constructing a strain for producing a recombinant protein containing unnatural amino acids, comprising:
- modifying the expression of a prfA gene contained in the strain to be controllable.
Dependencies are inferred from the claim text.