Device for separating motile cells

Abstract

The present disclosure relates to a mesoscale fluidic device for separating motile cells from non-motile cells, the mesoscale fluidic device including a substrate having a sample application compartment below a medium compartment, and a cell permeable filter with a pore size in the range of 1 μm to 20 μm, the cell permeable filter having an upper surface facing the medium compartment and a lower surface facing the sample application compartment, with the sample application compartment and the medium compartment being in fluid communication via the cell permeable filter, wherein the sample application compartment has a floor and at least one flow structure extending from the floor towards the lower surface of the cell permeable filter facing the sample application compartment. The device is especially useful for obtaining a medium enriched in motile sperm cells from a mammal sperm sample.

Dependencies are inferred from the claim text.