Nonameric peptide having excellent antibacterial activity against gram-negative bacteria and enantiomer thereof

Abstract

A nonameric peptide represented by an amino acid sequence of SEQ ID NO: 1 or its enantiomeric peptide thereof according to the present invention is low in cytotoxicity and excellent in terms of proteolytic stability, antimicrobial activity, and anti-inflammatory activity and has a remarkable therapeutic effect on Gram-negative bacterial infectious diseases, sepsis, or septic shock. Accordingly, the peptides can be advantageously applied to an antimicrobial composition, an anti-inflammatory composition, and a pharmaceutical composition for prevention or treatment of Gram-negative bacterial infectious diseases, sepsis, or septic shock.

Dependencies are inferred from the claim text.