Method and system for eye treatment

A method for delivering electrical-stimulation therapy to a patient, the method comprising:

• providing a first electrode substrate, wherein the first electrode substrate includes:
• one or more stimulation electrodes on the first electrode substrate that are configured to apply electrical stimulation signals to a first eye of the patient, the first eye having an upper eyelid and a lower eyelid;
• attaching the first electrode substrate to the patient's skin such that the one or more stimulation electrodes are on the outer surface of at least one of the upper eyelid and the lower eyelid of the first eye of the patient;
• providing a plurality of sensor electrodes including a first sensor electrode and a second sensor electrode;
• placing the first sensor electrode in a first selected location on the patient, and placing the second sensor electrode in a second selected location on the patient;
• providing a first return electrode;
• placing the first return electrode in a return location on the patient that provides a return path for the electrical stimulation signals applied by the one or more stimulation electrodes such that an electrical current is formed between at least one of the one or more stimulation electrodes and the first return electrode;
• delivering the electrical-stimulation therapy to the first eye, wherein the delivering includes controlling the electrical current formed between the at least one of the one or more stimulation electrodes and the first return electrode such that the electrical current passes through a retina of the first eye of the patient;
• and
• detecting, using the plurality of sensor electrodes, electrical activity from neural cells of the patient during the delivering of the electrical-stimulation therapy to the first eye, wherein the detecting of the electrical activity includes:
• detecting a difference in voltage between the first sensor electrode and the second sensor electrode in order to determine a characteristic of the electrical-stimulation therapy.

A non-transitory computer-readable medium having instructions stored thereon for causing a suitably programmed control system to execute a method for delivering electrical-stimulation therapy to a patient, the first eye having an upper eyelid and a lower eyelid, wherein the method is executed by the control system on an electrical-stimulation system that includes one or more stimulation electrodes on a first electrode substrate, wherein the one or more stimulation electrodes are configured to apply electrical stimulation signals to the first eye of the patient, wherein the first electrode substrate is attached to the patient's skin such that the one or more stimulation electrodes are on the outer surface at least one of the upper eyelid and the lower eyelid of the first eye of the patient, a plurality of sensor electrodes including a first sensor electrode placed in a first selected location on the patient and a second sensor electrode placed in a second selected location on the patient, a first return electrode that is placed in a return location on the patient that provides a return path for the electrical stimulation signals applied by the one or more stimulation electrodes such that an electrical current is formed between at least one of the one or more stimulation electrodes and the first return electrode, the method comprising:

• delivering the electrical-stimulation therapy to the first eye, wherein the delivering includes controlling the electrical current formed between the at least one of the one or more stimulation electrodes and the first return electrode such that the electrical current passes through a retina of the first eye of the patient;
• and
• detecting, via the plurality of sensor electrodes, electrical activity from neural cells of the patient during the delivering of the electrical-stimulation therapy to the first eye, wherein the detecting of the electrical activity includes:
• detecting a difference in voltage between the first sensor electrode and the second sensor electrode in order to determine a characteristic of the electrical-stimulation therapy.