Compositions for supplementing products with therapeutic agents and method of use thereof
OwnerAdam Garland, Brian R. SLOATinventors
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Abstract
Several embodiments pertain to nanoparticle-based compositions and their use in methods for the delivery of active agents to subjects and to products. In several embodiments, the compositions are stable for prolonged periods of time and under hot conditions and provide enhanced bioavailability and/or dispersibility.
Claims20
A nanoparticle composition comprising water at about 60 wt. % to about wt. 93.799% and at least one nanoparticle, the nanoparticle comprising:
- at least one active agent at 0.001 wt. % to 20 wt. %;
- at least one phospholipid at 5 wt. % to 20 wt. %;
- at least one triglyceride at 1 wt. % to 15 wt. %;
- at least one sterol at 0.2 wt. % to 2 wt. %;
- and
- optionally at least one surfactant at 0 wt. % to 17.5 wt. %,
- wherein the weight percentages are based on the weight of the composition.
A nanoparticle composition comprising water at about 60 wt. % to about wt. 93.799% and at least one nanoparticle, the nanoparticle comprising:
- at least one phospholipid at 5 wt. % to 20 wt. %;
- at least one triglyceride at 1 wt. % to 15 wt. %;
- at least one sterol at 0.2 wt. % to 2 wt. %;
- and
- optionally at least one surfactant at 0 wt. % to 17.5 wt. %,
- wherein the weight percentages are based on the weight of the composition.
A nanoparticle composition comprising water at about 0 wt. % to about wt. 10% and at least one nanoparticle, the nanoparticle comprising:
- at least one phospholipid at 10 wt. % to 50 wt. %;
- at least one triglyceride at 2 wt. % to 37.5 wt. %;
- at least one sterol at 0.4 wt. % to 5 wt. %;
- optionally at least one active agent at 0.002 wt. % to 50 wt. %;
- optionally at least one gum at 0.01 wt. % to 5 wt. %;
- and
- optionally at least one surfactant at 0 wt. % to 43.75 wt. %.
Dependencies are inferred from the claim text.