Use of mesencephalic astrocyte-derived neurotrophic factor in preparation of drug for treating herpes simplex keratitis
AssigneeEye Institute of Shandong First Medical University
InventorsLingling Yang, Zongzheng Zou, Xiaochuan Wang, Rong Chen, Jing Feng, Huifeng Wang
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Abstract
Disclosed is the use of a mesencephalic astrocyte-derived neurotrophic factor (Manf) in the preparation of a drug for treating herpes simplex keratitis (HSK). Manf has an anti-herpes simplex virus type I (HSV-1) effect and can inhibit corneal vascular proliferation, corneal inflammatory response, and corneal nerve regression caused by HSV-1 infection. Manf can be used to prepare drugs for treating the HSK.
Claims8
A method for treating a disease caused by herpes simplex virus (HSV), comprising a step of administering an HSV inhibitor containing mesencephalic astrocyte-derived neurotrophic factor (Manf) to a subject in need thereof.
A method for treating herpes simplex keratitis (HSK), comprising a step of administering an HSV inhibitor containing mesencephalic astrocyte-derived neurotrophic factor (Manf) to a subject in need thereof.
Dependencies are inferred from the claim text.