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AssigneeGenome and Company
InventorsHyerim KIM, Suro LEE, Jaesung YEON, Hyeyoung KIM, Donghun LEE
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The present invention relates to a novel Lactobacillus plantarum strain. In addition, the present invention relates to a composition for preventing, improving, or treating infertility or subfertility comprising the Lactobacillus plantarum strain. The Lactobacillus plantarum strain of the present invention reduces the expression of specific genes in cells constituting the placenta to help implantation of the embryo, increases the number of immune cells in the uterus, and enhances the implantation rate of embryos reduced by immune imbalance. Accordingly, it can be effectively utilized as a composition for the prevention, improvement, or treatment of infertility or subfertility.
A composition comprising at least one selected from the group consisting of a Lactobacillus plantarum strain deposited under Accession No. KCTC 14678BP, a culture of the strain, a fermentation product of the strain, a lysate of the strain, an extract of the strain and a cytoplasmic fraction obtained by lysing the strain, and carriers, excipients or diluents.
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Dependencies are inferred from the claim text.