Manipulation of tryptamine metabolism
AssigneeSeres Therapeutics, Inc.
InventorsEdward J. O'BRIEN, Asuncion MARTINEZ
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Abstract
Compositions and methods for altering tryptamine levels in a subject are provided. In general, the compositions comprise microorganisms.
Claims27
A method of altering a tryptamine level, a 5-hydroxytryptamine level, or both in a subject in need thereof, the method comprising administering a viable population of at least one bacterial species selected from Table 1, 2, 3, 4, 5, or 6 to the subject.
4-8. (canceled)
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A pharmaceutical formulation comprising a viable population of at least one bacterial species selected from Table 1, 2, 3, 4, 5, or 6, and a pharmaceutically acceptable excipient.
15-19. (canceled)
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A composition comprising at least two different bacterial species, wherein the combination of the at least two different bacterial species can synergistically increase a tryptamine level, a 5-hydroxytryptamine level, or both when administered to a subject.
34-39. (canceled)
Dependencies are inferred from the claim text.