Inhibitors of p1b-type atpases

A compound having one of the following formulae:

• a resonance structure thereof, or
• a pharmaceutically acceptable salt or aqueous solution or dispersion thereof,
• wherein each of R1, R2, and R3 individually are a halogen, hydrogen, hydroxyl, amine (NH2),
• or absent;
• wherein X1, X2, and X3 individually are a hydrogen, halogen, O, or C═O;
• wherein X4, X3, X6, and X7 individually are C or N;
• wherein at least two of X1, X2, and X3 are hydrogen;
• wherein Y is HC≡N, CH3, CH3—CH4, C═O, hydrogen, or absent;
• and
• wherein Z1, Z2, Z3, and Z4 individually are S, O, amine (NH2), —SH, —OH, —H, ═S, ═O, =amine (═NH2), or a protonated S, O, amine (NH2).