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US 2025/0017850 A1Published application
Salbutamol delivery formulations, devices and methods
AssigneeHoneywell International Inc.
InventorsERIK BOLDT, GREGORY LAURENCE SMITH
Life of this patent
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Abstract
Disclosed are medicinal compositions, and devices, methods and systems which use same, comprising a propellant and at least one medicinally active compound, said propellant comprising at least 1234ze(E) and ethanol.
Claims20
A pharmaceutical composition comprising:
- a. an active pharmaceutical ingredient (API) comprising salbutamol;
- b. from about 85% by weight to about 99% by weight of HFO-1234ze(E);
- c. from 1% by weight to about 15% by weight of ethanol;
- and
- d. from greater than 0.001% by weight to less than 0.1% by weight of oleic acid.
2 more elements
A pharmaceutical composition comprising:
- a. an active pharmaceutical ingredient (API) comprising salbutamol;
- b. from about 85% by weight to less than 99% by weight of HFO-1234ze(E);
- and
- c. from greater than 5% by weight to about 15% by weight of ethanol.
1 more element
A method of forming pharmaceutical compositions having improved stability, comprising forming a carrier comprising not more than 99% by weight HFO-1234ze and from greater than about 1% by weight to less than about 10% by weight of ethanol, and suspending in said carrier an API comprising salbutamol.
Dependencies are inferred from the claim text.