Mucosal Suction Patch and Uses Thereof in Drug Delivery

A mucosal suction patch having an external volume of between 50 μL and 5000 μL, the patch comprising

• at least one bulb forming at least one cavity, each of the at least one cavity being in fluid communication with at least one opening, and one or more of the at least one cavity enclosing a drug;
• a mucosa sealing surface delimiting the at least one opening;
• and
• a pressure applying surface opposite to the mucosa sealing surface;
• the at least one bulb having an elasticity such that, the at least one bulb being in an expanded state, upon applying mechanical pressure on the pressure applying surface, the at least one bulb is deformed, and when the mechanical pressure is released while the mucosa sealing surface is on a subject mucosa, the at least one bulb at least partially regains its expanded state, temporarily creating negative pressure inside the at least one cavity, which deforms the mucosa, which reversibly fills up at least part of the at least one bulb cavity, causing the drug to migrate in the mucosa.