Optical super-multiplexing by polyynes
AssigneeThe Trustees of Columbia University in the City of New York
InventorsWei MIN, Fanghao HU
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Abstract
A method for optical super-multiplexing using polyynes to provide enhanced images from stimulated Raman microscopy is disclosed. In some exemplary embodiments, the polyynes are organelle-targeted or spectral barcoded. Imaging can be enhanced by using the polyynes to image whole live cells or specific organelles within live cells. The polyynes can also be used in optical data storage (i.e., encoding) and identification (i.e., decoding) applications.
Claims11
A polyyne library comprising at least two types of polyynes chosen from the following structures:
- wherein in the above structures which comprise a hydroxymethyl group, the hydroxymethyl group is optionally absent.
A collection of beads having diameters of about 2 nm to about 100 μm and comprising polystyrene and having present in said beads one or more polyynes chosen from the following structures:
- wherein in the above structures which comprise a hydroxymethyl group, the hydroxymethyl group is optionally absent.
Dependencies are inferred from the claim text.