Drugs for treating neurodevelopmental disorders
AssigneesPresident and Fellows of Harvard College, Trustees of Tufts College
InventorsRichard Novak, Frederic Vigneault, Michael Levin, Donald E. Ingber
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Abstract
The present disclosure provides compositions and methods for treating neurodevelopmental disorders, such as Rett syndrome and cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder.
Claims21
1-51. (canceled)
A method of treating a symptom of a neurodevelopmental disorder in a subject in need thereof, the method comprising administering to the subject a therapeutically effective amount of an agent of Table 1.
A pharmaceutical composition comprising (a) two or more of vorinostat, ivermectin, trofinetide, and Bacteroides fragilis or a polysaccharide isolated from Bacteroides fragilis and (b) a pharmaceutically acceptable excipient.
Dependencies are inferred from the claim text.