Microfluidic System Including Cooling Device

A microfluidic system for separating biological entities comprising:

• a cooling device including a thermoelectric heat pump, a first fan, and a first heat exchanger disposed between the first fan and the thermoelectric heat pump;
• a first housing structure having a first shell that encases the first fan and the first heat exchanger, the first housing structure having first and second cavities that respectively expose two sides of the first heat exchanger and a third cavity formed adjacent to the first fan opposite the first heat exchanger;
• a microfluidic device and one or more piezoelectric transducers attached thereto;
• and
• a second housing structure reversibly attached to the first housing structure and having a second shell that encloses therein the microfluidic device and the one or more piezoelectric transducers, the second housing structure including fourth and fifth cavities that respectively expose two ends of the microfluidic device and a sixth cavity,
• wherein when the first and second housing structures are coupled, the first and second cavities are respectively aligned to the fourth and fifth cavities to form first and second air passages between the two sides of the first heat exchanger and the two ends of the microfluidic device, the third and sixth cavities are aligned to form a third air passage between the first fan and the one or more piezoelectric transducers, thereby allowing air to circulate between the third air passage and the first and second air passages.