Biocompatible self-healing polymers and uses thereof
AssigneeTechnion Research & Development Foundation Limited
InventorsHossam HAICK, Ning TANG
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AssigneeTechnion Research & Development Foundation Limited
InventorsHossam HAICK, Ning TANG
Estimating the term…
The present invention provides a self-healing biocompatible elastomer comprising polymeric chains comprising units of formula (A1), wherein R1 is selected from the group consisting of a linear (C2-C20) alkylene and —R4-S—S—R4′-, wherein R4 and R4′ are independently a linear (C1-C10) alkylene; R2 is a linear or cyclic (C4-C10) alkylene; and R3 is selected from the group consisting of a polybutadiene, a polybutene, a polyethylene, a polypropylene, and a polyisoprene, wherein the elastomer is crosslinked by hydrogen bonds between urethane linkages. Further provided is a one-pot method for preparing a self-healing biocompatible elastomer. The invention further provides an antibacterial composition and a wound dressing comprising the self-healing biocompatible elastomer. Formula (A1)
1-47. (canceled)
A self-healing biocompatible elastomer comprising polymeric chains comprising units of formula (A1)
A one-pot method for preparing a self-healing biocompatible elastomer, the method comprising reacting a hydroxyl-terminated polybutadiene (HTPB) with a linear or cyclic (C4-C10)alkylene diisocyanate compound and a hydroxyl-terminated compound selected from a linear (C2-C20)diol and a hydroxyl-terminated linear (C1-C10) alkyl disulfide.
Dependencies are inferred from the claim text.