Separation system and method for separating and purifying a target component

A separation system configured to process a fluid containing a plurality of components, wherein at least one component of the plurality of components of the fluid is a target component and wherein the separation system comprises:

• an aqueous-two phase extraction unit for aqueous-two phase extraction of the fluid;
• a separation unit for separating a target phase obtained after aqueous-two phase extraction, wherein the target phase contains the target component;
• and
• a crossflow diafiltration unit for continuous diafiltration of the separated target phase for obtaining a retentate and a permeate, wherein the crossflow diafiltration unit at least comprises a diafiltration channel, a first filter material, a retentate channel, a second filter material and a permeate collection channel, arranged in such a way that the first filter material delimits the diafiltration channel and the retentate channel from one another, and the second filter material delimits the retentate channel and the permeate collection channel from one another,
• wherein the diafiltration channel is connected in a fluid conducting manner to at least one inlet for a diafiltration medium, the retentate channel is connected in a fluid conducting manner to at least one inlet for the target phase and to at least one outlet for the retentate, and the permeate collection channel is connected in a fluid conducting manner to at least one outlet for the permeate.