Solid forms for tissue repair

A bi-phasic scaffold for tissue repair, the bi-phasic scaffold having two phases wherein:

• a first phase of the two phases comprises a series of hollows extending from an upper surface of the bi-phasic scaffold along a longitudinal axis in the first phase;
• wherein the hollows have a diameter ranging from about 125 to 650 mm and wherein the first phase has a height of between 1-7 mm;
• and
• a second phase of the two phases that is devoid of the series of hollows,
• wherein the first phase is atop the second phase, and wherein the bi-phasic scaffold is positioned such that the first phase is implanted within or proximally to cartilage tissue and the second phase is implanted within or proximally to bone tissue.

A method of inducing or enhancing repair, regeneration or enhancement of formation of cartilage, bone or a combination thereof, said method comprising implanting in a subject, a bi-phasic scaffold within a site in need of repair, regeneration or enhancement of formation of cartilage, bone or a combination thereof in said subject, wherein said bi-phasic scaffold has two phases wherein:

• a first phase of said two phases comprises a single piece of material and said first phase further comprises a series of hollows extending from an upper surface of the bi-phasic scaffold along a longitudinal axis in said first phase;
• and
• a second phase of said two phases comprises only the single piece of material, the second phase being devoid of the series of hollows,
• wherein each hollow of said hollows has a diameter ranging from about 125 to 650 um and wherein said first phase has a height of between 1-7 mm, wherein the first phase is atop the second phase, and wherein the bi-phasic scaffold is positioned such that the first phase is implanted within or proximally to cartilage tissue and the second phase is implanted within or proximally to bone tissue.