Bacteriophage preparations and methods of use
AssigneeThe Regents of the University of California
InventorsHenry C. Lin, Derek M. Lin, Britt Koskella
Life of this patent
Estimating the term…
Abstract
A bacteriophage preparation generally includes a preparation of a heterogeneous bacteriophages obtained from a fermentative process. The bacteriophage preparation may be formulated into a pharmaceutic composition. The bacteriophage preparation may be used to treat dysbiosis by administering the bacteriophage preparation to a subject having, or at risk of having, dysbiosis. The bacteriophage preparation may be used to prepare or prime the gut environment of a healthy subject prior to administering a source of bacteria to the subject.
Claims36
A pharmaceutical composition comprising:
- a preparation of a heterogeneous bacteriophages obtained from a fermentative process;
- and
- a pharmaceutically-acceptable carrier.
A method of preparing a bacteriophage preparation, the method comprising:
- isolating bacteriophage from a fermentative process;
- and
- combining the isolated bacteriophage with a pharmaceutically acceptable carrier.
(canceled)
A method of treating dysbiosis in a subject having, or at risk of having, dysbiosis, the method comprising:
- administering to the subject a bacteriophage preparation in an amount effective to ameliorate at least one symptom or clinical sign of dysbiosis.
21-27. (canceled)
(canceled)
(canceled)
A method of preparing or priming the gut environment of a healthy subject for administering a source of bacteria, the method comprising:
- administering to the subject a bacteriophage preparation in an amount effective to improve receptivity of subject's gut to the source of bacteria.
Dependencies are inferred from the claim text.