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US 2024/0407955 A1Published application
Dressing for treating hard-to-heal wounds and a process for the manufacture thereof
AssigneeWarszawski Uniwersytet Medyczny
InventorsMalgorzata LEWANDOWSKA-SZUMIEL, Ilona SZABLOWSKA-GADOMSKA, Stefan RUDZINSKI, Marta BOCHYNSKA-CZYZ, Tomasz GRZELA, Beata MROZIKIEWICZ-RAKOWSKA
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Abstract
A dressing is disclosed for treating hard-to-heal wounds and a process for the manufacture thereof, which may be useful in clinical practice, in particular for treating diabetic foot ulceration.
Claims14
A dressing for use in treating ulceration, in particular the diabetic foot, wherein said dressing consists of:
- a dressing material and
- ADSCs embedded therein,
- wherein the dressing material consists of a flat substrate having holes and an adhesive layer that coats its surface,
- wherein the flat substrate is made of a polymer containing polyester or polyurethane,
- while the adhesive layer contains a substance selected among of:
- silicone gel and a hydrocolloid containing carboxymethylcellulose or its salts with alkaline metals dispersed in a matrix containing petrolatum and paraffin oil.
3 more elements
A method for the manufacture of a dressing for use in treating ulceration, in particular the diabetic foot, characterized in that it includes stages in which:
- a) the dressing material is coated with fibronectin,
- b) ADSC suspension in a growth medium is applied on the surface of the fibronectin-coated dressing material,
- c) the cells are grown on the dressing material,
- d) the dressing material with the embedded ADSCs is separated and optionally stored frozen,
- wherein a dressing material is used that
- consists of a flat substrate having holes and an adhesive layer that coats its surface, wherein the flat substrate is made of an organic polymer containing polyester or polyurethane,
- while the adhesive layer contains a substance selected among of:
- silicone gel and a hydrocolloid containing carboxymethylcellulose or its salts with alkaline metals dispersed in a matrix containing petrolatum and paraffin oil.
5 more elements
Dependencies are inferred from the claim text.