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US 2024/0402194 A1Published application
Immunoassay for detecting neurodegenerative diseases pathology in biological fluids
AssigneeQatar Foundation for Education, Science and Community Development
InventorOmar El Agnaf
Life of this patent
Estimating the term…
Abstract
Antibodies and diagnostic assays for detecting synucleinopathies are provided. The assay is specific and compatible with different biological samples (brain, cerebrospinal fluid, blood, saliva, urine, skin, nasal swabs, or feces).
Claims18
An antibody, or fragments thereof, specific for α-synuclein aggregates, wherein the antibody has a variable light (VL) and a variable heavy (VH) amino acid sequence comprising:
- (a) a VL sequence of SEQ ID NO:2 and a VH sequence of SEQ ID NO:3;
- or
- (b) a VL sequence of SEQ ID NO:4 and a VH sequence of SEQ ID NO:5.
The antibody, or fragments thereof, wherein the antibody comprises a VL sequence of SEQ ID NO:2 and a VH sequence of SEQ ID NO:3.
Dependencies are inferred from the claim text.