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AssigneeBharat Biotech International Limited
InventorKrishna Murthy ELLA
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The invention discloses vaccine for coronavirus and influenza virus and method for preparation thereof. More specifically, the invention discloses seasonal viral vaccine i. e. coronavirus and influenza virus vaccine for prophylaxis of novel coronavirus (SARS-CoV-2) infection (COVID-19) and Influenza virus in mammals and method for preparation of such vaccine. The invention discloses the stable combination vaccine compositions of killed-inactivated SARS-CoV-2, Influenza virus (A and B strains) as antigens. The present invention further discloses method of adaptation and growth seasonal influenza (A and B) strains in cell culture and methods of inactivation and purification of influenza virus bulk antigen. The present invention also discloses SARS-CoV-2 vaccine formulation with inactivated Influenza viruses and use of the same to elicit immune response against the SARS-CoV-2 and Influenza viruses in mammals and humans.
A combined vaccine formulation comprising whole virion inactivated SARS-Cov-2 and quadrivalent influenza [A and B] antigens formulated with or without adjuvants in pharmaceutically acceptable buffer, wherein vaccine formulation elicits protective response against each of viruses in mammals.
A method of preparing a combined vaccine formulation comprising whole virion inactivated SARS-Cov-2 and influenza [A and B] antigens formulated with or without adjuvants in pharmaceutically acceptable buffer;
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