Method for detecting alzheimer's disease, and detection reagent
AssigneesYukifusa IGETA, Tosoh Corporation, Japanese Foundation for Cancer Research
InventorsKohei YUYAMA, Yukifusa IGETA, Koji UEDA
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Abstract
Provided are a method of simply detecting Alzheimer's disease (AD) and a method of simply stratifying AD pathological phases, and a reagent that can be used for the methods, based on the fact that measurement of a protein contained in extracellular vesicles enables detection of Alzheimer's disease and stratification of AD pathological phases.
Claims14
A method of detecting Alzheimer's disease, comprising the step of:
- measuring the quantity of a protein present in extracellular vesicles in a sample collected from a specimen,
- wherein the protein contained in the extracellular vesicles includes cathepsin B.
(canceled)
A method of detecting an amyloid accumulation phase of Alzheimer's disease, the method comprising the step of:
- measuring a protein contained in extracellular vesicles in a sample collected from a specimen,
- wherein the protein contained in the extracellular vesicles includes cathepsin B.
(canceled)
A method of detecting a Tau pathogenesis phase and/or a neurodegenerative phase of Alzheimer's disease, the method comprising the step of:
- measuring a protein contained in extracellular vesicles in a sample collected from a specimen,
- wherein the protein contained in the extracellular vesicles includes cathepsin B.
(canceled)
A diagnostic kit for Alzheimer's disease, comprising a reagent for measuring cathepsin B.
Dependencies are inferred from the claim text.