Multiplexed electronic immunoassay using enzymaticall amplified metallization on nanostructured surfaces
AssigneeGeorgia Tech Research Corporation
InventorsNeda Rafat, Aniruddh Sarkar, Hanhao Zhang
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Abstract
An exemplary embodiment of the present disclosure provides a system for detecting biomarkers. The system can comprise a composition a first electrode, a second electrode, and an electrical property sensor in electrical communication with the first electrode and the second electrode. The electrical property sensor can be configured to measure an electrical property of the composition. The composition can comprise a molecule of interest configured to bind with a target molecule in a biological sample, a probe molecule configured to bind with the target molecule, and a first metal particle configured to bind with the probe molecule.
Claims29
A composition comprising:
- a molecule of interest configured to bind with a target molecule in a biological sample;
- a probe molecule configured to bind with the target molecule;
- a first metal particle configured to bind with the probe molecule;
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- a second metal particle configured to amplify a binding of the first metal particle.
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Dependencies are inferred from the claim text.