Pig embryo-derived pluripotent stem cells and use thereof
AssigneeChina Agricultural University
InventorsJianyong HAN, Minglei ZHI, Jinying ZHANG
Life of this patent
Estimating the term…
Abstract
Pig embryo-derived pluripotent stem cells, having the characteristics and pluripotency of pig pre-gastrulation metaplasia epiblast cells. The solution is capable of stable passage, and is able to withstand multiple instances of consecutive gene editing and produce cloned pigs. The pig embryonic pluripotent stem cells create a new path for biological research, animal husbandry, and regenerative biomedicine.
Claims21
-35. (canceled)
A pluripotent stem cell, having a pluripotency of pig pre-gastrulation Epiblast cells, expressing one or more pluripotency markers and one or more Epiblast markers, and is capable of stable passage;
- 1 preferably, the pluripotent stem cell is derived from pig embryo.
Any of the following methods:
- (1) a method for producing a pig embryo;
- (2) a method for producing a cloned pig;
- (3) a method for producing a cell, a tissue or an organ (for example, an organoid) in vitro;
- (4) a method for preparing a disease model and/or a drug screening model.
Dependencies are inferred from the claim text.