Flow cell interface adaptor

A system for performing cyclic histology, the system comprising:

• a flow cell comprising:
• a first plate;
• a second plate;
• a gasket between the first and second plates, wherein the gasket includes an opening extending therethrough, the opening defined by a perimeter wall, such that an enclosed volume is formed by the first plate, the second plate, and the perimeter wall;
• and
• one or more fluid input holes in one of the first plate or the second plate, and one or more fluid output holes in the one of the first plate or the second plate, the one or more fluid input holes and one or more fluid output holes aligned with the enclosed volume, and
• a flow cell adaptor for use in cyclic histology, the flow cell adaptor having a body defining a cavity configured to removably receive a flow cell, wherein the adaptor has a fluid input channel configured to direct one or more reagents to a flow cell, and a fluid output channel configured to receive one or more reagents from a flow cell, wherein the flow cell adaptor comprises a heater configured to heat the one or more reagents in the fluid input channel wherein the fluid input channel is configured to direct one or more fluids to the one or more fluid input holes, and the fluid output channel is configured to receive one or more fluids from the one or more fluid output holes.