Loading patent…
AssigneeResearch & Business Foundation Sungkyunkwan University
InventorsJae Hyung PARK, Dong Gil YOU, Jae Yoon AN
Estimating the term…
The present invention relates to: a filler composition for reducing skin wrinkles, comprising stem cell-derived exosomes, hyaluronic acid, and BDDE; and a method for preparing same. The filler composition for reducing skin wrinkles according to the present invention not only overcome limitations of low in-vivo engraftment rate and survival rate of cells, which are the biggest problems of treatment using stem cells, but also suppresses side effects caused by tumorigenesis of stem cells and the like and exhibits an excellent collagen production effect, and it has been confirmed that the filler composition increases the proliferation of fibroblasts and collagen production by activating anti-inflammatory macrophages. Thus, the filler composition is expected to be effectively used in treatments for anti-aging, filler injections for cosmetic purposes, or the like.
A filler composition for reducing skin wrinkles, containing exosomes derived from stem cells, hyaluronic acid, and 1,4-butanediol diglycidyl ether (BDDE) as active ingredients.
A method for preparing a filler composition for reducing skin wrinkles, the method comprising steps of:
A method for reducing skin wrinkles, comprising a step of administering to a subject in need thereof a filler composition containing exosomes derived from stem cells, hyaluronic acid, and 1,4-butanediol diglycidyl ether (BDDE) as active ingredients.
Use of exosomes derived from stem cells, hyaluronic acid, and 1,4-butanediol diglycidyl ether (BDDE) for preparing a filler for reducing skin wrinkles.
Use of a filler composition containing exosomes derived from stem cells, hyaluronic acid, and 1,4-butanediol diglycidyl ether (BDDE) as active ingredients for reducing skin wrinkles.
Dependencies are inferred from the claim text.