Method of treating hepatitis c virus in patients
AssigneeAltesa BioSciences, Inc.
InventorsBrett Paul GIROIR, Katherine Elizabeth SQUIRES, John Michael CLERICI
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Abstract
The present disclosure describes methods of treating a hepatitis C virus (HCV) infection in a patient in need thereof by orally administering to the patient a therapeutically effective amount of a pharmaceutical composition, which may include one or more of compounds disclosed herein. The methods of treating the HCV infection in the patient may result in clearance of the HCV infection as measured by sustained virologic response.
Claims50
A method of treating a hepatitis C virus infection in a patient in need thereof comprising orally administering to the patient in need thereof, a therapeutically effective amount of a compound of Formula I:
- or a pharmaceutically acceptable salt thereof, thereby treating the hepatitis C virus infection in the patient.
A method of treating a hepatitis C virus infection in a patient in need thereof comprising orally administering to the patient a therapeutically effective amount of a compound of Formula I:
- or a pharmaceutically acceptable salt thereof, wherein administering a therapeutically effective amount of the compound of Formula I or a pharmaceutically acceptable salt thereof results in clearance of the hepatitis C virus infection.
A method of treating a hepatitis C virus infection in a patient in need thereof comprising orally administering to the patient a prodrug of Formula I:
- or a pharmaceutically acceptable salt thereof;
- wherein the prodrug is administered in an amount sufficient to result in a therapeutically effective amount of one or more of a compound of Formula II-VI in the liver of the patient:
- thereby treating the hepatitis C virus infection in the patient.
Dependencies are inferred from the claim text.