Hbv vaccine inducing pres-specific neutralizing antibodies
AssigneeViravaxx AG
InventorsInna TULAEVA, Carolin CORNELIUS-NIKL, Pia GATTINGER, Rudolf VALENTA
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Abstract
A Hepatitis B virus (HBV) vaccine comprising a fusion protein of a preS polypeptide fused to at least one grass pollen allergen peptide, for use in the treatment of a subject to induce HBV neutralizing antibodies, wherein the subject is an immune tolerant human subject and said treatment comprises repeated vaccination to break immune tolerance against HBV.
Claims24
A method of inducing HBV neutralizing antibodies in a subject comprising administering to the subject a Hepatitis B virus (HBV) vaccine comprising a fusion protein of a preS polypeptide fused to at least one grass pollen allergen peptide, wherein the subject is an immune tolerant human subject and said treatment comprises repeated vaccination to break immune tolerance against HBV.
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Dependencies are inferred from the claim text.