Multiple de novo designed protein binding proteins
AssigneeUniversity of Washington
InventorsLansing Joseph STEWART, David BAKER, Longxing CAO, Brian COVENTRY, Inna GORESHNIK, Buwei HUANG, Nathaniel BENNETT, Eva-Maria STRAUCH, Thomas SCHLICHTHAERLE
Life of this patent
Estimating the term…
Abstract
Designed polypeptides that bind specifically to a defined protein target are provided, as well as methods for their design and use.
Claims20
A polypeptide comprising an amino acid sequence at least 35% identical to the amino acid sequence selected from the group consisting of SEQ ID NO:1-1559 and 1561-1570, not including any functional domains added fused to the polypeptides (whether N-terminal, C-terminal, or internal), and wherein the 1, 2, 3, 4, or 5 N-terminal and/or C-terminal amino acid residues may be present or absent when considering the percent identity.
The method of claim 19, wherein the use comprises treating a tumor or infection.
(canceled)
Dependencies are inferred from the claim text.