Preformed lyophilization containers and methods of preparing the same
AssigneeTerumo BCT, Inc.
InventorsFrank CORBIN, Kestas Parakininkas, James Ladtkow
Life of this patent
Estimating the term…
Abstract
A lyophilization container includes a first section having a first layer, a second layer aligned with the first layer, and a cavity defined by the alignment of the first and second layers, where at least one of the first and second layers is preformed to have a three-dimensional shape. A lyophilization fixture includes a base member and a lid member. The lid member is movable between a first position and a second position relative to the base member. The base member and lid member together define a housing that receives at least a portion of a lyophilization container.
Claims20
A lyophilization container comprising:
- a first section including
- a first layer,
- a second layer aligned with the first layer, and
- a cavity defined by the alignment of the first and second layers, at least one of the first and second layers being preformed to have a three-dimensional shape.
A method for forming a lyophilization container, the method comprising:
- heating a sheet to a pliable temperature;
- disposing the sheet on or near a surface of a mold structure including a portion shaped to mold the sheet to form a layer having an open box configuration, the open box configuration including a planar surface and sides angled away from the planar surface;
- and
- cooling the layer to form the lyophilization container.
A method of using a lyophilization container, the method comprising:
- obtaining a lyophilization container, the lyophilization container including
- a first section including
- a first layer,
- a second layer aligned with the first layer, and
- a cavity defined by the alignment of the first and second layers, at least one of the first and second layers preformed to have a three-dimensional shape;
- and
- a second section including
- a third layer,
- a fourth layer aligned with the third layer, and
- a second cavity defined by the alignment of the third and fourth layers, at least one of the third and fourth layers including a breathable membrane;
- and
- disposing the lyophilization container in a lyophilization fixture, the lyophilization fixture including
- a first portion configured to support the first portion of the lyophilization container, the first portion including a base and a movable lid that together define a housing that receives the first portion of the lyophilization container;
- and
- a second portion configured to support the second portion of the lyophilization container.
Dependencies are inferred from the claim text.