Hyperpolarisation method and apparatus
AssigneeCambridge Enterprise Limited
InventorsArnaud COMMENT, Adam GAUNT
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AssigneeCambridge Enterprise Limited
InventorsArnaud COMMENT, Adam GAUNT
Estimating the term…
In a method for preparing a hyperpolarised sample, for example for carrying out a magnetic resonance technique, the sample is formed as a frozen layer (4) of a starting solution on a surface of a thermoconductive sample holder (1,2). The solution comprises molecules for hyperpolarisation, and photo-reactive molecules. Free radicals are induced in the frozen layer by exposing it to radiation. The sample is then hyperpolarised by dynamic nuclear polarization at a dynamic nuclear polarization temperature. After hyperpolarisation, the temperature of the sample is raised to a thermalisation or quenching temperature by thermal conduction of heat through the sample holder, to quench the free radicals. The polarised sample may then be stored for use, retaining its polarisation.
A method for preparing a hyperpolarised sample comprising the steps of:
An apparatus for handling a hyperpolarised sample, comprising a thermoconductive sample holder having a surface for, in use, carrying the sample in the form of a frozen layer, thermally couplable for the conduction of heat to and from a source of heat for controlling the temperature of the sample.
Dependencies are inferred from the claim text.