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US 2024/0368627 A1Published application
Gene therapy products facilitating bystander effects and methods using the same
AssigneeThe University of North Carolina at Chapel Hill
InventorsHaiyan Fu, Tierra Bobo
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Abstract
This invention relates to methods and compositions for gene therapy. In particular, the invention relates to compositions for enhancing delivery of therapeutic products to bystander cells that have not received the expression vector encoding the therapeutic product. The invention further relates to methods of treating disorders using the compositions of the invention.
Claims24
An expression vector comprising a polynucleotide encoding a nucleic acid of interest operably linked to an extracellular vesicle-targeting zip code sequence.
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Dependencies are inferred from the claim text.