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US 2024/0367165 A1Published application
Safe self-testing of multiplex biomarkers in biofluids
OwnerFrederic ZENHAUSERN, Ali FATTAHI +1inventors
InventorsFrederic ZENHAUSERN, Ali FATTAHI, Jerome LACOMBE
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Abstract
Provided herein are devices for self-testing for a plurality of biomarkers from a liquid biofluid sample. and related methods of using the devices to test for the biomarkers presence or absence. The devices comprise a specially configured vertical flow biosensor to provide a device platform that is safe and can be used at-home/in the field without need for any specialized equipment or external power sources.
Claims20
A device for self-testing for a plurality of biomarkers comprising:
- a sample inlet configured to receive a liquid biofluid sample;
- a sample pre-processing module fluidically connected to the sample inlet to provide a pre-processed biofluid sample;
- a filter in fluidic contact with the liquid biofluid sample or the pre-processing module to provide a filtered fluid sample;
- a powerless heat source in thermal contact with the pre-processed biofluid sample and/or the filtered fluid sample for controlled temperature of the pre-processed biofluid sample and/or filtered fluid sample;
- a vertical flow biosensor (VFB) comprising a multiplex membrane in fluidic contact with the pre-processed biofluid sample for multiplex detection of the plurality biomarkers in the liquid biofluid sample.
2 more elements
Dependencies are inferred from the claim text.