Inhibitor of prostate specific membrane antigen and pharmaceutical use thereof

A compound represented by formula (IV) or a pharmaceutically acceptable salt thereof,

• wherein:
• Q is selected from the group consisting of H and a protecting group, preferably from H;
• R1 and R2 are each independently selected from the group consisting of H and C1-4 alkyl and are preferably both H;
• the C1-4 alkyl is optionally substituted with one or more substituents P or is unsubstituted;
• each occurrence of Q, R1, and R2 may be the same or different;
• Y1 is S or O, preferably O;
• T is selected from the group consisting of —NR4(CO)—, —NR4 (SO2)—, and —NR4 (CH2)—;
• R4 is selected from the group consisting of H, C1-6 alkyl, 6-10 membered aryl, and 5-12 membered heteroaryl;
• the C1-6 alkyl, 6-10 membered aryl, or 5-12 membered heteroaryl is optionally substituted with one or more substituents P or is unsubstituted;
• ring A is selected from 3-12 membered nitrogen-containing heterocyclyl, wherein the 3-12 membered nitrogen-containing heterocyclyl is optionally substituted with one or more substituents P or is unsubstituted;
• W is selected from the group consisting of 6-10 membered aryl and 5-12 membered heteroaryl;
• the −10 membered aryl or 5-12 membered heteroaryl is optionally substituted with one or more substituents P or is unsubstituted;
• the substituents P are selected from the group consisting of C1-C6 alkyl, halogen, deuterium, hydroxy, sulfhydryl, —NRiRj, oxo, thio, —C(O)Rk, —C(O)ORk, —S(O)Rk, —S(O)ORk, —S(O)(O)Rk, —S(O)(O)ORk, —C(S)Rk, nitro, cyano, C1-C6 alkoxy, C1-C6 alkylthioether group, C2-C6 alkenyl, C2-C6 alkynyl, 3- to 10-membered cycloalkyl, 3- to 10-membered heterocyclyl, 6- to 10-membered aryl, 5- to 10-membered heteroaryl, 8- to 12-membered fused cycloaryl, and 5- to 12-membered fused heteroaryl;
• Ri and Rj are each independently selected from the group consisting of a hydrogen atom, hydroxy, C1-C6 alkyl, and C1-C6 alkoxy;
• Rk is independently selected from the group consisting of a hydrogen atom, C1-C6 alkyl, C1-C6 haloalkyl, C1-C6 alkoxy, hydroxy, and —NRiRj, wherein the alkyl, alkoxy, or haloalkyl is optionally substituted with one or more substituents selected from the group consisting of C1-C6 alkyl, halogen, hydrogen, sulfhydryl, —NRiRj, oxo, thio, carboxyl, nitro, cyano, C1-C6 alkoxy, C1-C6 alkylthioether group, C2-C6 alkenyl, C2-C6 alkynyl, 3- to 10-membered cycloalkyl, 3- to 10-membered heterocyclyl, 6- to 10-membered aryl, and 5- to 10-membered heteroaryl;
• y, z, g, and h are each independently integers of 0-6;
• R3 is selected from the group consisting of H and a chelating agent.