Expression of functional bacterial type i fatty acid synthase in photosynthetic hosts
AssigneeArizona Board of Regents on behalf of Arizona State University
InventorsWillem Vermaas, Tyson Burch
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Abstract
Provided herein are compositions and methods for expression of functional bacterial type I fatty acid synthase in photosynthetic hosts for production of activated acyl-CoAs and for use in biofuel production.
Claims12
A method for producing a modified cyanobacterium, the method comprising introducing into a cyanobacterium a heterologous gene encoding fatty acid synthase type I (FAS I), wherein the amount of activated acyl-CoA that is produced by the modified cyanobacterium is greater than that produced by the unmodified cyanobacterium.
A method for producing activated acyl-CoA, the method comprising the steps of:
- (a) introducing into a cyanobacterium a heterologous gene encoding fatty acid synthase type I (FAS I), thereby producing a modified cyanobacterium;
- and
- (b) culturing the modified cyanobacterium under conditions that promote activated acyl-CoA production by the cyanobacterium.
Dependencies are inferred from the claim text.