Anti-ptk7 single-domain antibody and application thereof
AssigneeNanomab Technology Limited
InventorsChung Lim WONG, Hong Hoi TING
Life of this patent
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Abstract
Provided are a set of specific single-domain antibody coding sequences targeting PTK7 and an application thereof. The provided anti-PTK7 single-domain antibody may effectively bind to a PTK7 antigen, which provides a basis for the research and development of drugs targeting PTK7, including radionuclide drug conjugates, antibody drug conjugates, multispecific antibody drugs and so on.
Claims18
A complementary determining region (CDR) of an anti-PTK7 single domain antibody VHH chain, wherein the complementary determining region (CDR) of the VHH chain comprises:
- CDR1 as shown in any one of SEQ ID Nos:
- 9-11;
- CDR2 as shown in any one of SEQ ID Nos:
- 12-14;
- and
- CDR3 as shown in any one of SEQ ID Nos:
- 15-18.
An anti-PTK7 single domain antibody, which is a single domain antibody against the PTK7 protein and has a VHH chain with an amino acid sequence shown in any one of SEQ ID NOs:
- 1-4.
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Dependencies are inferred from the claim text.