Biaryl kinase inhibitors
AssigneeBristol-Myers Squibb Company
InventorsGuanglin Luo, Carolyn Diane Dzierba, John E. Macor
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Abstract
The present disclosure is generally directed to compounds which can inhibit AAK1 (adaptor associated kinase 1), compositions comprising such compounds, and methods for inhibiting AAK1.
Claims2
A method of treating diabetic neuropathy, the method comprising administering to a patient in need thereof a therapeutically effective amount of (S)-1-((2′,6-bis(difluoromethyl)-[2,4′-bipyridin]-5-yl)oxy)-2,4-dimethylpentan-2-amine, or a pharmaceutically acceptable salt thereof, and LX-4211.
A pharmaceutical composition comprising (S)-1-((2′,6-bis(difluoromethyl)-[2,4′-bipyridin]-5-yl)oxy)-2,4-dimethylpentan-2-amine, or a pharmaceutically acceptable salt thereof, and LX-4211.
Dependencies are inferred from the claim text.