Systems And Methods For Shockwave Mediated Delivery Of Microvesicles And Stem Cells
AssigneeSynaptec Network, Inc.
InventorSheldon Jordan
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Abstract
Methods, systems, and devices are disclosed for facilitating delivery of microvesicles or stem cells across the blood brain barrier (BBB). A pressure device is used to target a region of a patient's brain. The pressure device delivers a shockwave to the targeted region, facilitating delivery of a microvesicle or stem cell at the targeted region. The shockwave does not damage brain tissue and does not disrupt or tear the BBB. A microvesicle or stem cell, or both, is administered to the patient and crosses the BBB at the targeted region, without damaging, tearing, or disrupting the BBB.
Claims20
A method of facilitating delivery of a structure to a patient's brain across the blood-brain barrier (BBB), comprising:
- targeting a region of the patient's brain with a pressure device;
- using the pressure device to induce a pressure wave in the region of the patient's brain and facilitate selective delivery of the structure to the region of the patient's brain;
- and
- administering the structure to the patient's blood stream, or spinal fluid space, or proximal to the BBB, wherein the structure traverses the BBB at the targeted region;
- wherein the structure is one of a microvesicle or a stem cell.
Dependencies are inferred from the claim text.