Loading patent…
AssigneeUniversity of Houston System
InventorsBradley K. McConnell, Robert J. Schwartz, Nicole Prodan
Estimating the term…
The present disclosure pertains to compositions suitable for use in differentiating cardiac progenitor cells to cells that resemble cardiac Purkinje cells. Additional embodiments pertain to methods of generating such differentiated cardiac cells by exposing cardiac progenitor cells to the compositions. The present disclosure also pertains to methods of treating or preventing a cardiovascular disease in a subject by administering the compositions or differentiated cardiac cells to the subject. Further embodiments pertain to methods of generating a cardiac tissue by exposing cardiac progenitor cells to a composition of the present disclosure and associating the cardiac progenitor cells with a tissue scaffold. The present disclosure also pertains to the use of the differentiated cardiac progenitor cells to assess the efficacy of one or more compounds in the treatment or prevention of a cardiovascular disease. The present disclosure also pertains to the differentiated cardiac cells and cardiac tissues that include them.
A composition comprising the following compounds:
(canceled)
7-8. (canceled)
A method of generating differentiated cardiac cells, said method comprising:
(canceled)
21-21. (canceled)
A method of treating or preventing a cardiovascular disease in a subject, said method comprising:
(canceled)
29-29. (canceled)
43-43. (canceled)
Dependencies are inferred from the claim text.